Publications

10. HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells

Muralidharan, R.; Mehta, M.; Ahmed, R.; Roy, S.; Xu, L.; Aubé, J.; Chen, A.; Zhao, Y.; Herman, T.; Ramesh, R.*; Munshi, A.*

Scientific Reports 7, 2017, Article number: 9694.

 


Prior to Ole Miss

9. N-Phenylbenzamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore

Roy, S.; Sileikyte, J.; Neuenswander, B.; Hedrick, M. P.; Chung, T. D. Y.; Aubé, J.; Schoenen, F. J.*; Forte M. A.*; Bernardi, P.*

ChemMedChem, 2016, 11, 283–288.

 

8. Discovery, Synthesis, and Optimization of Diarylisoxazole-3-carboxamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore

Roy, S.; Sileikyte, J.; Schiavone, M.; Neuenswander, B.; Argenton, F.; Aubé, J.; Hedrick, M. P.; Chung, T. D. Y.; Forte M. A.; Bernardi, P.; Schoenen, F. J.

ChemMedChem, 2015, 10, 1655–1671.

 

7. A Practical and Scalable Synthesis of (S)- and (R)-1-(Dimethoxyphosphoryl)allyl Methyl Carbonates

Roy, S.; Sutivisedsak, N.; Hamper, B. C.; Lyss, A. M.; Spilling, C. D.

Synthesis, 2015, 47, 3669–3672.

 

6. Small Molecules Targeting the Mitochondrial Permeability Transition

Sileikyte, J.; Roy, S.; Porubsky, P.; Neuenswander, B.; Wang, J.; Hedrick, M.; Pinkerton, A. B.; Salaniwal, S.; Kung, P.; Mangravita-Novo, A.; Smith, L. H.; Bourdette, D. N.; Jackson, M. R.; Aubé, J; Chung, T. D. Y.; Schoenen, F. J.; Forte M. A.; Bernardi, P.

Probe Reports from the NIH Molecular Libraries Program. Submitted in April, 2014; Peer-reviewed in July, 2014.

 

5. Development of (E)-2-((1,4-dimethylpiperazin-2-ylidene)amino)-5-nitro-N-phenylbenzamide, ML336: Novel 2-Amidinophenylbenzamides as Potent Inhibitors of Venezuelan Equine Encephalitis Virus

Schroeder, C. E.; Yao, Y.; Sotsky, J.; Smith, R. A.; Roy, S.; Chu, Y-K, Guo, H.; Tower, N. A.; Noah, J. W.; McKellip, S.; Sosa, M.; Ramussen, L.; Smith, L. H.; White. E. L.; Aubé, J.; Jonsson, C. B.; Chung, D.; Golden, J. E.

Journal of Medicinal Chemistry, 2014, 57, 8608–8621.

 

4. ML336: Development of Quinazolinone-Based Inhibitors Against Venezuelan Equine Encephalitis Virus (VEEV)

Chung, D.; Schroeder, C. E.; Sotsky, J.; Yao, T.; Roy, S.; Smith, R. A.; Tower, N. A.; Noah, J. A.; McKellip, S.; Sosa, M.; Rasmussen, L.; White, E. L.; Aubé, J.; Golden, J. E.

Probe Reports from the NIH Molecular Libraries Program. Submitted in December, 2012; Peer-reviewed in February, 2013.

 

 

2. Synthesis of the C(18)-C(34) Fragment of Amphidinolide C and the C(18)-C(29) Fragment of Amphidinolide F

Roy, S.; Spilling, C. D.

Organic Letters, 2010, 12, 5326–5329.

 

1. A Task Specific Basic Ionic Liquid, [BmIm]OH-promoted Efficient green and One-pot Synthesis of Tetrahydrobenzo[b]pyran Derivatives

Ranu, B. C.; Banerjee, S.; Roy, S.

Indian Journal of Chemistry, 2008, 47B, 1108–1112.

 


Patent

1. Small Molecule Inhibitors of the Mitochondrial Permeability Transition Pore (mtPTP)

Roy, S.; Bernardi, P.; Forte, M. A.; Schoenen, F. J.; Sileikyte, J.

PCT Int. Appl. (2016), WO 2016073633 A1 20160512.